Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581981 | 0.85 | KMT2A (0.43) | CYP4F2CYP4A11MAPTALDH1A1GAA | |
| SCHEMBL13575460 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11SMN1; SMN2PKMMAPT | |
| SCHEMBL23653466 | 0.81 | KMT2A (0.48) | CYP4F2CYP4A11SMN1; SMN2PKMMAPT | |
| SCHEMBL28315461 | 0.80 | CYP4F2 (0.45) | CYP4F2CYP4A11SMN1; SMN2PKMMAPT | |
| SCHEMBL29274373 | 0.75 | LTB4R (0.43) | SMN1; SMN2MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL27538658 | 0.75 | MAPT (0.44) | CYP4F2CYP4A11MAPTALDH1A1GAA | |
| SCHEMBL16048513 | 0.74 | CYP4F2 (0.47) | CYP4F2CYP4A11SMN1; SMN2PKMMAPT | |
| SCHEMBL12688394 | 0.73 | CYP4F2 (0.47) | CYP4F2CYP4A11MAPTCYP4Z1ALDH1A1 | |
| SCHEMBL6759614 | 0.73 | CYP4F2 (0.53) | CYP4F2CYP4A11SMN1; SMN2PKMMAPT | |
| SCHEMBL1504839 | 0.72 | ALDH1A1 (0.55) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| CN-117089533-A | Recombinant carbonyl reductase, mutant, coding gene and application thereof | 浙江工业大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-105039361-B | Carbonyl reduction enzyme gene, codase, carrier, bacterial strain and application | 浙江工业大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-105039361-B | Carbonyl reduction enzyme gene, codase, carrier, bacterial strain and application | 浙江工业大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-105039361-A | Carbonyl reductase gene, codase, vector, strain and application of gene | UNIV ZHEJIANG TECHNOLOGY | 2015-11-11 | — | — | CN | disclosed |
| CN-100510093-C | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | SALTIGO GMBH (DE) | 2009-07-08 | — | — | CN | disclosed |
| CN-1694878-A | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | AVECIA LTD (GB) | 2005-11-09 | — | — | CN | disclosed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | disclosed |