SCHEMBL27583153

SCHEMBL27583153

CCc1ccccc1C(=O)OC(O)CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 1/20 0.48
KMT2A Q03164 1/20 0.44
TSHR P16473 4/20 0.43
ALDH1A1 P00352 8/20 0.41
LMNA P02545 3/20 0.41
CLCN2 P51788 1/20 0.41
CYP3A4 P08684 2/20 0.39
CA2 P00918 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
SCN1A P35498 2/20 0.38
SCN2A Q99250 2/20 0.38
SCN3A Q9NY46 2/20 0.38
HSD17B10 Q99714 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
PRSS1 P07477 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28490442 0.95 UTS2R (0.45) UTS2RKMT2ATSHRALDH1A1LMNA
SCHEMBL1513963 0.89 TSHR (0.53) KMT2ATSHRALDH1A1LMNACYP3A4
SCHEMBL28102299 0.85 KMT2A (0.48) KMT2ATSHRALDH1A1LMNACYP3A4
SCHEMBL27713909 0.84 UTS2R (0.49) UTS2RKMT2ATSHRALDH1A1LMNA
SCHEMBL29267594 0.84 KMT2A (0.38) UTS2RKMT2ATSHRALDH1A1LMNA
SCHEMBL10591636 0.83 TSHR (0.52) TSHRALDH1A1LMNACYP3A4CA2
SCHEMBL28362466 0.83 LMNA (0.55) KMT2ATSHRALDH1A1LMNACA2
SCHEMBL27637585 0.83 SMN1; SMN2 (0.48) UTS2RKMT2ATSHRALDH1A1LMNA
SCHEMBL1513969 0.83 ALDH1A1 (0.56) KMT2ATSHRALDH1A1LMNACYP3A4
SCHEMBL873754 0.83 TSHR (0.50) KMT2ATSHRALDH1A1LMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1728995-A Dosage forms comprising a cetp inhibitor and an HMG-CoA reductase inhibitor PFIZER PROD INC (US) 2006-02-01 CN claimed
CN-1545421-A Pharmaceutical composition comprising a low-solubility and/or acid-sensitive drug and a neutralized acidic polymer �Ʒ� 2004-11-10 CN claimed
CN-1523979-A Pharmaceutical compositions of adsorbates of amorphous drug �Ʒ� 2004-08-25 CN claimed
CN-1418089-A Pharmaceutical composition of glycogen phosphorylase inhibitor PFIZER PROD INC (US) 2003-05-14 CN claimed
CN-1402629-A Pharmaceutical compositions providing enhanced drug concentrations PFIZER PROD INC (US) 2003-03-12 CN claimed
CN-107303278-B HC-1119 solid dispersion and preparation method thereof 成都海创药业有限公司 2020-11-13 CN disclosed
CN-107548302-A Viscosity building compositions for personal care products 奥麒个人护理产品有限合伙公司 2018-01-05 CN disclosed
CN-102802608-A Dosage forms of apixaban PFIZER 2012-11-28 CN disclosed
CN-102695413-A Stable fatty acid formulations MYCELL HOLDINGS LTD 2012-09-26 CN disclosed
CN-102026612-A Modification of particulate-stabilised fluid-fluid interfaces UNILEVER PLC 2011-04-20 CN disclosed
CN-101573110-A Methods of lowering glucose levels SANOFI AVENTIS DEUTSCHLAND (DE) 2009-11-04 CN disclosed
CN-101175477-A Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same KING PHARMACEUTICALS RES & DEV (US) 2008-05-07 CN disclosed
CN-1688291-A Immediate release dosage forms containing solid drug dispersions PFIZER (US) 2005-10-26 CN disclosed
CN-1681479-A Pharmaceutical compositions of semi-ordered drugs and polymers PFIZER PROD INC (US) 2005-10-12 CN disclosed
CN-1625397-A Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor PFIZER PROD INC (US) 2005-06-08 CN disclosed
CN-1545421-A Pharmaceutical composition comprising a low-solubility and/or acid-sensitive drug and a neutralized acidic polymer �Ʒ� 2004-11-10 CN disclosed
CN-1523979-A Pharmaceutical compositions of adsorbates of amorphous drug �Ʒ� 2004-08-25 CN disclosed
CN-1458840-A Pharmaceutical composition of cholesteryl ester transfer protein inhibitor PFIZER PROD INC (US) 2003-11-26 CN disclosed
CN-1418089-A Pharmaceutical composition of glycogen phosphorylase inhibitor PFIZER PROD INC (US) 2003-05-14 CN disclosed
CN-1402629-A Pharmaceutical compositions providing enhanced drug concentrations PFIZER PROD INC (US) 2003-03-12 CN disclosed