Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583153 | 0.95 | UTS2R (0.48) | UTS2RKMT2AALDH1A1LMNACLCN2 | |
| SCHEMBL1513963 | 0.85 | TSHR (0.53) | KMT2AALDH1A1LMNATSHRKDM4E | |
| Acetic Acid SCHEMBL28478365 | 0.84 | LMNA (0.50) | KMT2AALDH1A1LMNATSHRKDM4E | |
| SCHEMBL1513969 | 0.82 | ALDH1A1 (0.56) | KMT2AALDH1A1LMNATSHRKDM4E | |
| SCHEMBL28102299 | 0.81 | KMT2A (0.48) | KMT2AALDH1A1LMNATSHRCA2 | |
| SCHEMBL27713909 | 0.80 | UTS2R (0.49) | UTS2RKMT2AALDH1A1LMNACLCN2 | |
| SCHEMBL29267594 | 0.80 | KMT2A (0.38) | UTS2RKMT2AALDH1A1LMNACLCN2 | |
| SCHEMBL18669147 | 0.79 | UTS2R (0.46) | UTS2RKMT2AALDH1A1LMNACLCN2 | |
| SCHEMBL10591636 | 0.79 | TSHR (0.52) | ALDH1A1LMNATSHRKDM4EHPGD | |
| SCHEMBL28362466 | 0.79 | LMNA (0.55) | KMT2AALDH1A1LMNATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437947-A | Non-pig formulations and methods thereof | 第一浪潮生物制药有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114206319-B | Pharmaceutical composition for treating HBV | 组装生物科学股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116437947-A | Non-pig formulations and methods thereof | 第一浪潮生物制药有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115697336-A | Pharmaceutical preparation and use thereof | 奥尔德拉医疗公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-107303278-B | HC-1119 solid dispersion and preparation method thereof | 成都海创药业有限公司 | 2020-11-13 | — | — | CN | disclosed |