Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585456 | 0.83 | KMT2A (0.51) | MEN1KMT2AALDH1A1HPGDGAA | |
| Isophthalic Acid SCHEMBL27516105 | 0.82 | USP30 (0.53) | MEN1KMT2AALDH1A1HPGDGAA | |
| Isophthalic Acid SCHEMBL27899309 | 0.81 | HPGD (0.61) | MEN1KMT2AALDH1A1HPGDGAA | |
| Benzene SCHEMBL27525227 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL4696934 | 0.80 | L3MBTL3 (0.72) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL27583244 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL15076720 | 0.78 | L3MBTL3 (0.70) | MEN1KMT2AALDH1A1HPGDGAA | |
| Isophthalic Acid SCHEMBL5406230 | 0.78 | HPGD (0.57) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL17573006 | 0.78 | EPHX2 (0.52) | MEN1KMT2ARAB9A | |
| Isophthalic Acid SCHEMBL27265495 | 0.78 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1404481-A | Nicotinamide benzofused heterocyclic derivatives useful as selective inhibitors of PDE4 isozymes | PFIZER PROD INC (US) | 2003-03-19 | — | — | CN | disclosed |