Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.40 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12279980 | 0.88 | GPR35 (0.51) | KDM4EGPR35PTPN1ARBAZ2B | |
| SCHEMBL1823757 | 0.86 | GPR35 (0.52) | KDM4EGPR35PTPN1ARBAZ2B | |
| Hydrochloric Acid SCHEMBL1825977 | 0.84 | GPR35 (0.51) | KDM4EGPR35PTPN1ARBAZ2B | |
| SCHEMBL18952893 | 0.81 | GPR35 (0.59) | KDM4EGPR35PTPN1MEN1KMT2A | |
| SCHEMBL2482769 | 0.79 | SRPK1 (0.51) | KDM4EGPR35PTPN1ARMEN1 | |
| SCHEMBL10338606 | 0.79 | SRPK1 (0.51) | KDM4EGPR35PTPN1ARMEN1 | |
| SCHEMBL25273104 | 0.78 | ALDH1A1 (0.55) | KDM4EKMT2APPARGLMNAALOX15 | |
| SCHEMBL1823348 | 0.78 | ALDH1A1 (0.55) | KDM4EKMT2APPARGLMNAALOX15 | |
| SCHEMBL10024278 | 0.77 | KDM4E (0.54) | KDM4EPTPN1DHODHFTO | |
| SCHEMBL10024261 | 0.77 | PTPN1 (0.55) | KDM4EPTPN1DHODHFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1529706-A | Piperazine derivatives | - | 2004-09-15 | — | — | CN | claimed |
| CN-1780612-B | Treatment of incontinence with 5HT2C agonists. | PFIZER | 2010-12-01 | — | — | CN | disclosed |
| CN-1780612-A | Treatment of incontinence with 5HT2C agonists. | PFIZER (US) | 2006-05-31 | — | — | CN | disclosed |