Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273104 | 1.00 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL11957029 | 0.94 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL19313385 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL25273103 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL12123475 | 0.90 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL16141469 | 0.89 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL15307581 | 0.88 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL15594582 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL15569597 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTKEAP1KMT2A | |
| SCHEMBL1823757 | 0.83 | GPR35 (0.52) | ALDH1A1GAAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017577-B2 | Indacenodithiophene and indacenodiselenophene polymers and their use as organic semiconductors | MERCK PATENT GMBH (DE) | 2015-04-28 | — | — | US | disclosed |
| EP-2315793-B1 | INDACENODITHIOPHENE AND INDACENODISELENOPHENE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2013-08-21 | — | — | EP | disclosed |
| US-20110226999-A1 | Indacenodithiophene and Indacenodiselenophene Polymers and their Use as Organic Semiconductors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-09-22 | — | — | US | disclosed |
| EP-2315793-A1 | INDACENODITHIOPHENE AND INDACENODISELENOPHENE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS | Merck Patent GmbH (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010020329-A1 | INDACENODITHIOPHENE AND INDACENODISELENOPHENE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH, (DE) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110226999-A1 | Indacenodithiophene and Indacenodiselenophene Polymers and their Use as Organic Semiconductors | ICMT, TST, INMT | ALDH1A1 1672/4885GAA 4848/4885MAPT 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.