Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27573306 | 0.86 | THRB (0.38) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL2398722 | 0.84 | THRB (0.37) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Bromide SCHEMBL27831872 | 0.79 | TSHR (0.39) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27804221 | 0.73 | HPGD (0.30) | TSHRHPGD | |
| Hydrochloric Acid SCHEMBL27481277 | 0.73 | TSHR (0.37) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28340564 | 0.72 | TSHR (0.38) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL2398902 | 0.71 | THRB (0.38) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1108008 | 0.71 | TSHR (0.43) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL302801 | 0.71 | THRB (0.43) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL27615636 | 0.71 | TSHR (0.38) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1419571-A | Aqueous saline dispersions of water-soluble copolymers based on cationic monomers, method for the production thereof and use thereof | ATOFINA (FR) | 2003-05-21 | — | — | CN | disclosed |
| CN-1395584-A | Saline aqueous dispersions of water soluble (CO) polymers based on cationic monomers, method for making same and uses thereof | ATOFINA (FR) | 2003-02-05 | — | — | CN | disclosed |