SCHEMBL275865

SCHEMBL275865

[O]C1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.41
HTR6 P50406 1/20 0.40
CYP2D6 P10635 2/20 0.39
KDM4E B2RXH2 4/20 0.37
HSD17B10 Q99714 3/20 0.37
TP53 P04637 2/20 0.37
CYP3A4 P08684 2/20 0.37
LMNA P02545 2/20 0.37
BRD4 O60885 1/20 0.37
CCL2 P13500 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
DRD2 P14416 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
NFKB1 P19838 1/20 0.37
CHRM3 P20309 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345741 0.76 ALDH1A1 (0.35) KDM4EHSD17B10TP53CYP3A4MEN1
SCHEMBL194746 0.75 HTR2A (0.38) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL5698322 0.74 HTR2A (0.44) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL2512254 0.73 HTR2A (0.33) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL6233907 0.72 HTR2A (0.43) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL31046607 0.72 HTR2A (0.43) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL19630560 0.71 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
Carbon Monoxide SCHEMBL4154235 0.71 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL23071395 0.70 HTR2A (0.41) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL5954133 0.70 HTR2A (0.41) HTR2AHTR6CYP2D6KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240027927-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-01-25 US disclosed
EP-4310593-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM Business Innovation Corp. (JP) 2024-01-24 EP disclosed
CN-117434803-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2024-01-23 CN disclosed
US-20240012343-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-01-11 US disclosed
EP-4303660-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM Business Innovation Corp. (JP) 2024-01-10 EP disclosed
CN-117369230-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2024-01-09 CN disclosed
US-20230333493-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-10-19 US disclosed
CN-116774539-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2023-09-19 CN disclosed
WO-2023169096-A1 POSITIVE ELECTRODE ACTIVE MATERIAL, SECONDARY BATTERY, BATTERY MODULE, BATTERY PACK, AND ELECTRIC DEVICE 宁德时代新能源科技股份有限公司 2023-09-14 WO disclosed
CN-116741953-A Positive electrode active material, secondary battery, and electricity device 宁德时代新能源科技股份有限公司 2023-09-12 CN disclosed
US-6432993-B1 BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 2002-08-13 US disclosed
EP-1178996-A1 METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS THE DOW CHEMICAL COMPANY (US) 2002-02-13 EP disclosed
CN-1287117-A Cyclobutene derivatives, preparation method and therapeutic use thereof SANKYO CO (JP) 2001-03-14 CN disclosed
EP-1070703-A1 Cyclobutene derivatives Sankyo Company Limited (JP) 2001-01-24 EP disclosed
WO-2000069870-A1 METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS THE DOW CHEMICAL COMPANY (US) 2000-11-23 WO disclosed
EP-1022272-A1 SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS Sankyo Company Limited (JP) 2000-07-26 EP disclosed
EP-0413464-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
EP-0413465-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
US-4981827-A Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-01 US disclosed
EP-0323082-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-07-05 EP disclosed