Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953631 | 0.79 | DPP4 (0.38) | MAPTALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL15515534 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL5451713 | 0.76 | ALDH1A1 (0.35) | MAPTALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL7427319 | 0.76 | LMNA (0.38) | MAPTALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL27736992 | 0.75 | CHRM2 (0.31) | — | |
| SCHEMBL2482014 | 0.75 | MAPT (0.33) | MAPTALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL5452862 | 0.73 | ALDH1A1 (0.33) | MAPTALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL2484108 | 0.72 | MAPT (0.32) | MAPT | |
| SCHEMBL2481859 | 0.72 | MAPT (0.32) | MAPT | |
| SCHEMBL31412188 | 0.72 | GLA (0.44) | MAPTALDH1A1LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1390219-A | Pyrazolopyrimidines as therapeutic agents | ABBOTT AG (DE) | 2003-01-08 | — | — | CN | disclosed |