Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854441 | 0.85 | MGLL (0.58) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL11063253 | 0.81 | MGLL (0.61) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL531154 | 0.81 | MAPT (0.65) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL11060689 | 0.81 | MGLL (0.61) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL29277468 | 0.81 | MGLL (0.57) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL11064813 | 0.81 | MGLL (0.61) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL60448 | 0.80 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL7073161 | 0.80 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL28120256 | 0.80 | MGLL (0.56) | MGLLBCL9CTNNB1MAPTCRHBP | |
| SCHEMBL28063044 | 0.80 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1398247-A | Colchicol derivatives as vascular damaging agents | ANGIOGENE PHARM LTD (GB) | 2003-02-19 | — | — | CN | disclosed |