Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | CCR8 | P51685 | 4/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1071469 | 0.81 | SMN1; SMN2 (0.43) | LMNACCR1CCR8CCR5TSHR | |
| SCHEMBL6131342 | 0.79 | CCR1 (0.39) | LMNACCR1CCR8CCR5TSHR | |
| SCHEMBL28517555 | 0.78 | KDM4E (0.54) | LMNACCR1CCR8CCR5TSHR | |
| Hydrochloric Acid SCHEMBL1070025 | 0.72 | LMNA (0.40) | LMNACCR1CCR8CCR5TSHR | |
| Hydrochloric Acid SCHEMBL1072267 | 0.69 | CCR1 (0.40) | LMNACCR1CCR8CCR5TSHR | |
| Hydrochloric Acid SCHEMBL1071824 | 0.69 | MAPT (0.40) | LMNACCR1CCR8CCR5TSHR | |
| SCHEMBL6131362 | 0.68 | LMNA (0.42) | LMNACCR1CCR8CCR5TSHR | |
| Hydrochloric Acid SCHEMBL819577 | 0.68 | KDM4E (0.41) | LMNACCR1CCR8CCR5TSHR | |
| Hydrochloric Acid SCHEMBL1069659 | 0.67 | CCR1 (0.40) | LMNACCR1CCR8CCR5TSHR | |
| Hydrochloric Acid SCHEMBL5009057 | 0.65 | P2RX7 (0.40) | LMNACCR1CCR8CCR5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100354287-C | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with donor bridge | BASSEL POLYOLEFIN AG (DE) | 2007-12-12 | — | — | CN | disclosed |
| CN-1399640-A | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with donor bridge | BASSEL POLYOLEFIN AG (DE) | 2003-02-26 | — | — | CN | disclosed |