Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29846304 | 0.77 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL9266052 | 0.75 | PKM (0.55) | KDM4EALDH1A1PKM | |
| SCHEMBL22932534 | 0.75 | TP53 (0.50) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL11548041 | 0.74 | TP53 (0.53) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL1546661 | 0.73 | TP53 (0.52) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL1547296 | 0.71 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL4557326 | 0.71 | MAPT (0.44) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| Bromide SCHEMBL5138476 | 0.70 | MAPT (0.43) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL29979999 | 0.69 | CYP3A4 (0.55) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL5619009 | 0.69 | CYP3A4 (0.55) | KDM4ESMN1; SMN2ALDH1A1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1412181-A | Carboxylic acid derivatives inhibiting the binding of integrins to their receptors | TEXAS BIOTECHNOLOGIES CORP (US) | 2003-04-23 | — | — | CN | disclosed |