Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5138476 | 0.98 | MAPT (0.43) | MAPTKMT2ACYP1A2HTTATM | |
| SCHEMBL2032135 | 0.81 | MAPT (0.52) | MAPTKMT2ACYP1A2HTTKCNN4 | |
| SCHEMBL15228211 | 0.75 | MAPT (0.48) | MAPTKMT2ACYP1A2HTTKCNN4 | |
| Water SCHEMBL28078270 | 0.74 | MAPT (0.47) | MAPTKMT2ACYP1A2HTTKCNN4 | |
| SCHEMBL7067742 | 0.73 | MAPK1 (0.41) | KMT2ACYP1A2KCNN4ALDH1A1KDM4E | |
| SCHEMBL29097238 | 0.73 | KMT2A (0.42) | MAPTKMT2ACYP1A2HTTKCNN4 | |
| SCHEMBL24781345 | 0.71 | ALDH1A1 (0.40) | MAPTKMT2AHTTKCNN4CYP2C19 | |
| SCHEMBL28205550 | 0.71 | CYP2C19 (0.43) | MAPTKMT2ACYP1A2KCNN4CHRM2 | |
| SCHEMBL27587403 | 0.71 | KDM4E (0.44) | MAPTKMT2AHTTLMNAALDH1A1 | |
| SCHEMBL3827840 | 0.70 | ALDH1A1 (0.46) | KMT2ACYP1A2HTTKCNN4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096119-A1 | SALTS 669 | ASTRAZENECA AB (SE) | 2008-08-14 | — | — | WO | claimed |
| EP-2124941-A1 | COMBINATION OF A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2-ADRENOCEPTOR AGONIST | Argenta Discovery Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008096126-A1 | COMBINATION OF A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2-ADRENOCEPTOR AGONIST | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |