SCHEMBL27587474

SCHEMBL27587474

CCc1ncc(OC(CC)CC)nc1CC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 2/20 0.35
MCHR1 Q99705 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27570699 0.90
SCHEMBL7477808 0.80
SCHEMBL27570700 0.77 MCHR1 (0.35) MCHR1
SCHEMBL4882689 0.68 CRHR1 (0.33) CRHR1
SCHEMBL4881240 0.68 GCK (0.34) CRHR1MCHR1
SCHEMBL28750598 0.67 GABRP (0.41)
SCHEMBL19121107 0.67 KDM4E (0.39) MCHR1
SCHEMBL756047 0.65 KDM4E (0.35) CRHR1
SCHEMBL29832120 0.65 KDM4E (0.35) CRHR1
SCHEMBL251411 0.65 MAPKAPK2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1400970-A Substituted arylpyrazines NEUROGEN CORP (US) 2003-03-05 CN claimed