Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL668244 | 0.94 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNANAAA | |
| Salicylic Acid SCHEMBL17710452 | 0.92 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDLMNANAAA | |
| Salicylic Acid SCHEMBL3468302 | 0.92 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDLMNANAAA | |
| Phthalic Acid SCHEMBL5048545 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDLMNACA2 | |
| Salicylic Acid SCHEMBL29794306 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDLMNANAAA | |
| Salicylic Acid SCHEMBL28753449 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDLMNANAAA | |
| Cinnamic Acid SCHEMBL669104 | 0.86 | MAPT (0.48) | KDM4EALDH1A1HPGDLMNAGAA | |
| Salicylic Acid SCHEMBL28753451 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDLMNANAAA | |
| Salsalate SCHEMBL668243 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HPGDLMNANAAA | |
| Salicylic Acid SCHEMBL30395570 | 0.85 | LMNA (0.44) | KDM4EALDH1A1HPGDLMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742976-B1 | LOW-VISCOSITY ALLOPHANATES HAVING ACTINICALLY HARDENABLE GROUPS | BAYER MATERIALSCIENCE AG (DE) | 2010-09-15 | — | — | EP | claimed |
| EP-1727846-B1 | PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS | BAYER MATERIALSCIENCE AG (DE) | 2009-09-16 | — | — | EP | claimed |
| US-7381785-B2 | Preparation of new radiation-curing binders | BAYER METERIALSCIENCE AG (DE) | 2008-06-03 | — | — | US | claimed |
| US-7361723-B2 | Low-viscosity allophanates containing actinically curable groups | BAYER MATERIALSCIENCE AG (DE) | 2008-04-22 | — | — | US | claimed |
| EP-1742976-A1 | LOW-VISCOSITY ALLOPHANATES HAVING ACTINICALLY HARDENABLE GROUPS | Bayer MaterialScience AG (DE) | 2007-01-17 | — | — | EP | claimed |
| EP-1727846-A1 | PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS | Bayer MaterialScience AG (DE) | 2006-12-06 | — | — | EP | claimed |
| WO-2005092943-A1 | PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS | BAYER MATERIALSCIENCE AG (DE) | 2005-10-06 | — | — | WO | claimed |
| WO-2005092942-A1 | LOW-VISCOSITY ALLOPHANATES HAVING ACTINICALLY HARDENABLE GROUPS | BAYER MATERIALSCIENCE AG (DE) | 2005-10-06 | — | — | WO | claimed |
| US-20050209427-A1 | Low-viscosity allophanates containing actinically curable groups | BAYER MATERIALSCIENCE AG | 2005-09-22 | — | — | US | claimed |
| US-20050209361-A1 | Preparation of new radiation-curing binders | BAYER MATERIALSCIENCE AG | 2005-09-22 | — | — | US | claimed |
| WO-2024204416-A1 | COMPOUND, ANTISEPTIC AGENT, ANTIBACTERIAL AGENT, COMPOSITION, METHOD FOR PRODUCING ANTISEPTICIZED MATERIAL, AND METHOD FOR PRODUCING ANTIBACTERIAL-TREATED MATERIAL | 富士フイルム株式会社 | 2024-10-03 | — | — | WO | disclosed |
| US-20240058452-A1 | PHARMACEUTICAL COMPOSITION CONTAINING TEMPERATURE-RESPONSIVE IONIC LIQUID | TORAY INDUSTRIES, INC. (JP) | 2024-02-22 | — | — | US | disclosed |
| CN-114502142-B | Pharmaceutical composition comprising temperature responsive ionic liquid | 东丽株式会社 | 2023-05-09 | — | — | CN | disclosed |
| EP-4043007-A1 | PHARMACEUTICAL COMPOSITION INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID | Toray Industries, Inc. (JP) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502142-A | Pharmaceutical compositions comprising temperature-responsive ionic liquids | 东丽株式会社 | 2022-05-13 | — | — | CN | disclosed |
| US-20050209427-A1 | Low-viscosity allophanates containing actinically curable groups | BAYER MATERIALSCIENCE AG | 2005-09-22 | — | — | US | disclosed |
| US-20050209361-A1 | Preparation of new radiation-curing binders | BAYER MATERIALSCIENCE AG | 2005-09-22 | — | — | US | disclosed |
| US-20050143270-A1 | Cleaning solutions and etchants and methods for using same | SACHEM, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2005045895-A2 | CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME | SACHEM, INC. (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2003082976-A1 | THERMOSETTING RESIN COMPOSITION AND EPOXY RESIN MOLDING MATERIAL USING THE COMPOSITION AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240058452-A1 | PHARMACEUTICAL COMPOSITION CONTAINING TEMPERATURE-RESPONSIVE IONIC LIQUID | SULT1A1, CYP2C19, SULT2A1 | KDM4E 3065/4885ALDH1A1 1394/4885HPGD 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.