Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605987 | 0.85 | PARG (0.50) | PKMRXFP1ALDH1A1KDM4EHPGD | |
| SCHEMBL27605944 | 0.84 | PARG (0.55) | PKMRXFP1ALDH1A1KDM4EHPGD | |
| SCHEMBL6245488 | 0.83 | MMP13 (0.60) | PKMALDH1A1GAAMAPTPARG | |
| SCHEMBL27588029 | 0.82 | PARG (0.52) | MAPTPARGTP53MMP13SLC22A8 | |
| SCHEMBL7634243 | 0.81 | TP53 (0.57) | MAPTPARGTP53MMP13SLC22A8 | |
| SCHEMBL7103213 | 0.81 | PARG (0.52) | PKMRXFP1ALDH1A1KDM4EHPGD | |
| SCHEMBL27588009 | 0.81 | PARG (0.54) | RXFP1PARGTP53TSHRMMP13 | |
| SCHEMBL7097504 | 0.81 | PARG (0.57) | RXFP1PARGTP53TSHRMMP13 | |
| SCHEMBL27588021 | 0.81 | PARG (0.54) | RXFP1PARGTP53TSHRMMP13 | |
| SCHEMBL27588034 | 0.81 | PARG (0.52) | PKMALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1537105-A | Quinazolines useful as MMP-13 inhibitors | ��������ʲ��������ι�˾ | 2004-10-13 | — | — | CN | disclosed |