Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 15/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588258 | 0.85 | PKM (0.56) | PARGRXFP1PKMKDM4EALDH1A1 | |
| SCHEMBL27605944 | 0.82 | PARG (0.55) | PARGRXFP1PKMKDM4EALDH1A1 | |
| SCHEMBL27588009 | 0.81 | PARG (0.54) | PARGRXFP1 | |
| SCHEMBL27588021 | 0.81 | PARG (0.54) | PARGRXFP1 | |
| SCHEMBL6245488 | 0.81 | MMP13 (0.60) | PARGPKMALDH1A1GAAMAPT | |
| SCHEMBL27605948 | 0.80 | PARG (0.66) | PARGRXFP1PKMKDM4EALDH1A1 | |
| SCHEMBL7627149 | 0.80 | MAPT (0.51) | RXFP1KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL27588029 | 0.80 | PARG (0.52) | PARGMAPT | |
| SCHEMBL7097504 | 0.79 | PARG (0.57) | PARGRXFP1 | |
| SCHEMBL7103213 | 0.79 | PARG (0.52) | PARGRXFP1PKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1537105-A | Quinazolines useful as MMP-13 inhibitors | ��������ʲ��������ι�˾ | 2004-10-13 | — | — | CN | disclosed |