Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | RORC | P51449 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128794 | 0.85 | MEN1 (0.69) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7128929 | 0.85 | RAB9A (0.67) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7130345 | 0.84 | MEN1 (0.73) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL7127621 | 0.83 | ABL1 (0.63) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL27571288 | 0.83 | ADORA3 (0.71) | HSP90AA1KMT2AMEN1MAPTLMNA | |
| SCHEMBL27571249 | 0.82 | MAPT (0.71) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL19435568 | 0.82 | RAB9A (0.61) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7127473 | 0.82 | RORC (0.61) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7125386 | 0.82 | RAB9A (0.59) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7130323 | 0.81 | RORC (0.63) | KMT2AMEN1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440383-A | PPAR gamma modulators | SANKYO CO (JP) | 2003-09-03 | — | — | CN | disclosed |