Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28004633 | 0.84 | ALDH1A1 (0.48) | DRD3CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL14586768 | 0.84 | DRD3 (0.54) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL8282502 | 0.82 | CHRM2 (0.47) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL29108908 | 0.81 | DRD3 (0.51) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL8282488 | 0.80 | KMT2A (0.49) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL4550356 | 0.78 | DRD3 (0.59) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL17740871 | 0.78 | DRD3 (0.55) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL20715508 | 0.78 | KCNH2 (0.41) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL27572400 | 0.77 | ATM (0.51) | TDP1LMNASMN1; SMN2 | |
| SCHEMBL23823660 | 0.77 | CYP1A2 (0.64) | DRD3PIK3CDCYP1A2TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1434802-A | New azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-08-06 | — | — | CN | disclosed |
| CN-1434870-A | Viral core protein-cationic lipid-nucleic acid-delivery complexes | MITSUBISHI PHARMACEUTICALS INC (JP) | 2003-08-06 | — | — | CN | disclosed |