Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14586768 | 0.85 | DRD3 (0.54) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL17740871 | 0.83 | DRD3 (0.55) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL9980789 | 0.83 | ALDH1A1 (0.49) | DRD3HRH3SLC29A1ALDH1A1KDM4E | |
| SCHEMBL27590902 | 0.81 | DRD3 (0.50) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL4550356 | 0.79 | DRD3 (0.59) | DRD3PIK3CDCYP1A2TDP1CYP4F2 | |
| SCHEMBL29025304 | 0.79 | ALDH1A1 (0.41) | HSD11B1SLC29A1ALDH1A1KDM4E | |
| SCHEMBL11344621 | 0.79 | USP2 (0.45) | ALDH1A1USP2 | |
| SCHEMBL167666 | 0.79 | L3MBTL1 (0.52) | DRD3CYP1A2HRH3SIGMAR1ALDH1A1 | |
| SCHEMBL23823660 | 0.78 | CYP1A2 (0.64) | DRD3PIK3CDCYP1A2TDP1HRH3 | |
| SCHEMBL23634797 | 0.78 | DRD3 (0.54) | DRD3PIK3CDCYP1A2TDP1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |