Sugi Predict

Sugi Predict / Compounds / SCHEMBL4550356

SCHEMBL4550356

SCHEMBL4550356

COCCN1CCN(C(C)=O)CC1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ DRD3 P35462 3/20 0.59
▸ HSD11B1 P28845 1/20 0.55
▸ PIK3CD O00329 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ CYP4F2 P78329 1/20 0.45
▸ CYP4A11 Q02928 1/20 0.45
▸ HRH3 Q9Y5N1 1/20 0.43
▸ NAMPT P43490 1/20 0.42
▸ KDM1A O60341 2/20 0.42
▸ DRD2 P14416 1/20 0.42
▸ SIGMAR1 Q99720 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.40
▸ THRB P10828 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ USP2 O75604 1/20 0.40
▸ ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14104123 0.93 DRD3 (0.54) DRD3HSD11B1PIK3CDCYP1A2TDP1
SCHEMBL6043046 0.89 DRD3 (0.53) DRD3HSD11B1PIK3CDCYP1A2TDP1
SCHEMBL8260854 0.85 DRD3 (0.56) DRD3HSD11B1PIK3CDCYP1A2TDP1
SCHEMBL3052320 0.84 HSD11B1 (0.55) DRD3HSD11B1TDP1NAMPTDRD2
SCHEMBL17740871 0.84 DRD3 (0.55) DRD3HSD11B1PIK3CDCYP1A2TDP1
SCHEMBL23823660 0.83 CYP1A2 (0.64) DRD3PIK3CDCYP1A2TDP1HRH3
SCHEMBL3939911 0.82 HSD11B1 (0.54) DRD3HSD11B1TDP1NAMPTDRD2
SCHEMBL3216394 0.82 HSD11B1 (0.54) DRD3HSD11B1TDP1NAMPTDRD2
SCHEMBL23634797 0.82 DRD3 (0.54) DRD3HSD11B1PIK3CDCYP1A2TDP1
SCHEMBL5962390 0.82 HSD11B1 (0.58) DRD3HSD11B1TDP1NAMPTDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746414-B Aza-quinoline compounds and uses thereof 诺华公司 2024-10-18 — — CN claimed
EP-4034535-A1 AZA-QUINOLINE COMPOUNDS AND USES THEREOF Novartis AG (CH) 2022-08-03 — — EP claimed
CN-114746414-A Aza-quinoline compounds and uses thereof 诺华公司 2022-07-12 — — CN claimed
CN-114746414-B Aza-quinoline compounds and uses thereof 诺华公司 2024-10-18 — — CN disclosed
US-11914248-B2 Photo-alignment copolymer, photo-alignment film, and optical laminate FUJIFILM CORPORATION (JP) 2024-02-27 — — US disclosed
US-20230213695-A1 LAMINATES, POLARIZING PLATES, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-20230217789-A1 OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-20230141212-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS DICE ALPHA, INC. 2023-05-11 — — US disclosed
US-11635558-B2 Optical laminate and image display device FUJIFILM CORPORATION (JP) 2023-04-25 — — US disclosed
EP-4034535-A1 AZA-QUINOLINE COMPOUNDS AND USES THEREOF Novartis AG (CH) 2022-08-03 — — EP disclosed
CN-114746414-A Aza-quinoline compounds and uses thereof 诺华公司 2022-07-12 — — CN disclosed
US-20100111900-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS ROCHE PALO ALTO LLC 2010-05-06 — — US disclosed
US-20090054407-A1 Nitrogen-containing heterocyclic compound KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-02-26 — — US disclosed
US-20090054407-A1 Nitrogen-containing heterocyclic compound KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-02-26 — — US disclosed
US-7465726-B2 Substituted pyrrolo[2.3-B]pyridines OSI PHARMACEUTICALS, INC. (US) 2008-12-16 — — US disclosed
WO-2008092861-A1 BICYCLIC DERIVATIVES AS EP4 AGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 2008-08-07 — — WO disclosed
EP-1880993-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-01-23 — — EP disclosed
US-20070129364-A1 Pyrrolopyridine kinase inhibiting compounds OSI PHARMACEUTICALS, INC. 2007-06-07 — — US disclosed
US-20070037739-A1 Compounds useful in coating stents to prevent and treat stenosis and restenosis MEDLOGICS DEVICE CORPORATION (US) 2007-02-15 — — US disclosed
US-20070037739-A1 Compounds useful in coating stents to prevent and treat stenosis and restenosis MEDLOGICS DEVICE CORPORATION (US) 2007-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054407-A1 Nitrogen-containing heterocyclic compound NR4A1, NR5A2, PRMT8 DRD3 170/4885HSD11B1 533/4885PIK3CD 4159/4885
US-20230141212-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS IL17A, IL2, IL23R DRD3 4316/4885HSD11B1 822/4885PIK3CD 1737/4885
US-20100111900-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS POLR2A, EIF2AK2, POLR2B DRD3 1674/4885HSD11B1 1977/4885PIK3CD 1813/4885
US-20070129364-A1 Pyrrolopyridine kinase inhibiting compounds BMX, ERBB2, FRK DRD3 3859/4885HSD11B1 4267/4885PIK3CD 130/4885
US-20070037739-A1 Compounds useful in coating stents to prevent and treat stenosis and restenosis CAD, DBNL, DCAF15 DRD3 2196/4885HSD11B1 1935/4885PIK3CD 2776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.