Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15164727 | 0.91 | PDE10A (0.69) | PDE10AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7147056 | 0.88 | PDE10A (0.60) | PDE10AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15819453 | 0.83 | PDE10A (0.50) | PDE10AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1892283 | 0.81 | MAPT (0.48) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL1892286 | 0.81 | MAPT (0.48) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL14114993 | 0.80 | LMNA (0.64) | PDE10AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL21119271 | 0.80 | MAPT (0.58) | MAPT | |
| SCHEMBL15826339 | 0.79 | HTR7 (0.49) | PDE10A | |
| SCHEMBL14115045 | 0.79 | MEN1 (0.61) | PDE10AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5578378 | 0.79 | PDE10A (0.58) | PDE10AMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1575177-A | Cxcr3 antagonists | TULARIK INC (US) | 2005-02-02 | — | — | CN | disclosed |