Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.39 |
| ▸ | CEPT1 | Q9Y6K0 | 4/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613973 | 0.91 | MAPT (0.41) | MAPTESR2CETPHDAC6ESR1 | |
| SCHEMBL27595006 | 0.90 | CASP3 (0.42) | MAPTESR2CETPESR1ALDH1A1 | |
| SCHEMBL27595010 | 0.90 | ACP1 (0.44) | ESR2ALDH1A1HPGDSMN1; SMN2CHRNA7 | |
| SCHEMBL27595003 | 0.90 | VSIR (0.40) | MAPTCEPT1HDAC6ALDH1A1HPGD | |
| SCHEMBL27595031 | 0.90 | PPARG (0.44) | MAPTESR2ESR1SMN1; SMN2RXFP1 | |
| SCHEMBL27595030 | 0.88 | HDAC6 (0.43) | MAPTESR2CETPHDAC6ESR1 | |
| SCHEMBL27613934 | 0.86 | ESR2 (0.35) | MAPTESR2ESR1ALDH1A1HPGD | |
| SCHEMBL27595097 | 0.85 | MAPT (0.44) | MAPTALDH1A1HPGDSMN1; SMN2RXFP1 | |
| SCHEMBL27614030 | 0.84 | RET (0.41) | MAPTHDAC6ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27595009 | 0.84 | ALDH1A1 (0.44) | MAPTESR2CETPESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100425600-C | Benzothiazole-and benzo \\58743, oxazole-4, 7-dione derivatives and their use as CDC25 phosphatase inhibitors | SOD CONSEILS RECH APPLIC (FR) | 2008-10-15 | — | — | CN | claimed |
| CN-1610675-A | Benzothiazole- and benzoxazole-4,7-dione derivatives and their use as CDC25 phosphatase inhibitors | SOD CONSEILS RECH APPLIC (FR) | 2005-04-27 | — | — | CN | claimed |
| CN-100425600-C | Benzothiazole-and benzo \\58743, oxazole-4, 7-dione derivatives and their use as CDC25 phosphatase inhibitors | SOD CONSEILS RECH APPLIC (FR) | 2008-10-15 | — | — | CN | disclosed |
| CN-1610675-A | Benzothiazole- and benzoxazole-4,7-dione derivatives and their use as CDC25 phosphatase inhibitors | SOD CONSEILS RECH APPLIC (FR) | 2005-04-27 | — | — | CN | disclosed |