Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25024454 | 0.78 | LMNA (0.38) | LMNAHTT | |
| SCHEMBL30233803 | 0.78 | LMNA (0.38) | LMNAHTT | |
| SCHEMBL27614371 | 0.73 | LMNA (0.34) | LMNAHTT | |
| SCHEMBL30934584 | 0.72 | KDM4E (0.38) | — | |
| SCHEMBL25212351 | 0.72 | KDM4E (0.38) | — | |
| SCHEMBL2628953 | 0.71 | KMO (0.35) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL25024456 | 0.70 | ROCK2 (0.37) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL30234055 | 0.70 | ROCK2 (0.37) | LMNAHTTSMN1; SMN2 | |
| Potassium Ion SCHEMBL1763104 | 0.70 | KMO (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL27563129 | 0.65 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101229164-B | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | BRISTOL MYERS SQUIBB CO | 2013-01-02 | — | — | CN | disclosed |
| CN-100384423-C | Compositions and antiviral activity of substituted azaindoloxoacetylpiperazine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-100379421-C | Compositions and antiviral activity of substituted azaindoloxoacetylpiperazine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2008-04-09 | — | — | CN | disclosed |
| CN-1688311-A | Compositions and antiviral activity of substituted azaindoloxoacetylpiperazine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2005-10-26 | — | — | CN | disclosed |
| CN-1612763-A | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2005-05-04 | — | — | CN | disclosed |