Fluorobenzene

Fluorobenzene

SCHEMBL27595608

CCOC(=O)CF.Fc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GAA P10253 2/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CASP3 P42574 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
PPID Q08752 1/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Propionate SCHEMBL27460954 0.87 MEN1 (0.49) MAPTMEN1KMT2ALMNACYP1A2
Malonic Acid Diethyl Ester SCHEMBL28030450 0.87 GAA (0.58) MAPTMEN1KMT2ALMNACYP1A2
Phenol SCHEMBL28224536 0.85 GAA (0.50) MAPTMEN1KMT2AGAATSHR
Bromobenzene SCHEMBL27444449 0.84 KMT2A (0.46) MAPTMEN1KMT2ALMNANPSR1
Iodobenzene SCHEMBL27493646 0.84 MEN1 (0.46) MEN1KMT2AGAATSHRSMN1; SMN2
Aniline SCHEMBL27466974 0.84 LMNA (0.49) MEN1KMT2ALMNACYP1A2GAA
Fluorobenzene SCHEMBL27833809 0.82 GAA (0.47) MAPTMEN1KMT2ALMNACYP1A2
Anisole SCHEMBL28187460 0.82 CA4 (0.48) MAPTMEN1KMT2ALMNACYP1A2
Acetophenone SCHEMBL27462192 0.82 L3MBTL1 (0.47) MAPTMEN1KMT2ALMNANPSR1
Fluorobenzene SCHEMBL28152955 0.81 ALDH1A1 (0.56) MAPTMEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1436463-A Synthesis process of primisulfuron-methy and other fluoric hebicide XIAO SHENCHU (CN) 2003-08-20 CN claimed