Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595787 | 0.87 | HTR2A (0.34) | LMNACNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL28751429 | 0.86 | CNR2 (0.36) | CNR2CYP19A1MEN1KMT2A | |
| SCHEMBL65457 | 0.84 | CACNA2D1 (0.37) | LMNAHTTCNR2MITFCNR1 | |
| SCHEMBL14198825 | 0.78 | IDO1 (0.46) | LMNAKMT2A | |
| SCHEMBL15577528 | 0.78 | HTR2A (0.41) | LMNAMAPK1NPSR1ALDH1A1TDP1 | |
| SCHEMBL27614458 | 0.77 | LMNA (0.36) | LMNAMEN1KMT2ACACNA2D1CACNA1B | |
| SCHEMBL6962007 | 0.76 | SERPINH1 (0.41) | LMNAHTTCNR2CNR1MAPK1 | |
| SCHEMBL23960436 | 0.73 | CYP19A1 (0.46) | CNR2CYP19A1FFAR1CACNA2D1CACNA1B | |
| SCHEMBL2088573 | 0.69 | CYP19A1 (0.40) | HTTCYP19A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3136328 | 0.69 | GABBR2 (0.43) | HTTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589261-A | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5) | ASTRAZENECA AB (SE) | 2005-03-02 | — | — | CN | disclosed |