Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647312 | 0.84 | KMT2A (0.51) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL11310955 | 0.74 | ALDH1A1 (0.51) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL4441748 | 0.74 | CA2 (0.44) | KMT2ATDP1MEN1ALDH1A1HSD11B1 | |
| SCHEMBL28753955 | 0.72 | CTSL (0.50) | KMT2ASMN1; SMN2ALDH1A1LMNAATM | |
| SCHEMBL27614871 | 0.71 | ALDH1A1 (0.50) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL1081063 | 0.70 | KDM4E (0.49) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL11288690 | 0.69 | GSK3B (0.62) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL11754044 | 0.69 | KDM4E (0.54) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL15282567 | 0.68 | ALDH1A1 (0.45) | MAPTKMT2AKDM4EMAPK1TDP1 | |
| SCHEMBL12559833 | 0.67 | MAPT (0.52) | MAPTKMT2AKDM4EMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100484928-C | thiadiazoline derivatives | KYOWA HAKKO KOGYO KK FUJI PHOT (JP) | 2009-05-06 | — | — | CN | disclosed |
| CN-1617864-A | thiadiazoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 2005-05-18 | — | — | CN | disclosed |