SCHEMBL2759778

SCHEMBL2759778

CCOC(=O)OC1=C(c2c(C)cc(Br)cc2C)C(=O)NC12CCN(OC)CC2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.33
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2759750 0.92 CYP1A2 (0.33) MEN1MAPK1KMT2A
SCHEMBL15300245 0.91 ACACB (0.35) MEN1KMT2A
SCHEMBL2759777 0.90
SCHEMBL2759779 0.88 ADAM17 (0.32)
SCHEMBL14998135 0.88
SCHEMBL19275124 0.88 MEN1 (0.35) FPR2MEN1KMT2A
SCHEMBL2759796 0.87 TDP2 (0.37) FPR2MEN1MAPK1KMT2A
SCHEMBL14998132 0.87
SCHEMBL2759758 0.85 ACACB (0.36) FPR2MEN1MAPK1KMT2A
SCHEMBL2759798 0.85 ACACB (0.42) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352375-B1 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2015-03-25 EP disclosed
US-8722578-B2 Spiroheterocyclic pyrrolidinedione herbicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2014-05-13 US disclosed
US-8722578-B2 Spiroheterocyclic pyrrolidinedione herbicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2014-05-13 US disclosed
US-20120004105-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2012-01-05 US disclosed
US-20120004105-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2012-01-05 US disclosed
WO-2010052161-A2 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2010-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004105-A1 HERBICIDAL COMPOSITIONS DDT, CAT, HDHD5 FPR2 3795/4885MEN1 4823/4885MAPK1 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.