Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.63 |
| ▸ | ITGAV | P06756 | 13/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.63 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.63 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.63 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598291 | 0.95 | ITGB3 (0.62) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL4919562 | 0.79 | ITGB3 (0.67) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| Hydrochloric Acid SCHEMBL4071123 | 0.78 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6177908 | 0.77 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6771845 | 0.75 | ITGB3 (0.71) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL18056099 | 0.75 | ITGB3 (0.77) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176461 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176963 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176936 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL27598293 | 0.73 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1471512-A | Geminally substituted alphavβ3Integrin antagonists | — | 2004-01-28 | — | — | CN | claimed |
| CN-1471512-A | Geminally substituted alphavβ3Integrin antagonists | — | 2004-01-28 | — | — | CN | disclosed |