SCHEMBL27598677

SCHEMBL27598677

CC(C)(C(N)=O)C(C)(CC(=O)O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.44
CHRM1 P11229 1/20 0.44
TBXA2R P21731 1/20 0.44
ADRA1A P35348 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CYP2C19 P33261 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
FFAR1 O14842 1/20 0.38
CPT2 P23786 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
BHMT Q93088 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7156289 0.74 HMGCR (0.42) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL804144 0.72 KDM4E (0.54) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL6534968 0.72 CYP2C19 (0.62) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL16249744 0.71 TSHR (0.60) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL233792 0.70 CYP2C19 (0.52) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL4152740 0.69 LMNA (0.43) TSHRTDP1ALDH1A1MAPTKMT2A
T-Butylacetic Acid SCHEMBL28024820 0.69 HMGCR (0.52) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL6412305 0.68 CYP2C19 (0.50) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL23560607 0.67 TSHR (0.55) HMGCRCHRM1TBXA2RADRA1AKDM4E
SCHEMBL4200264 0.67 HMGCR (0.44) HMGCRCHRM1TBXA2RADRA1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1663944-A Process for preparing acetamides compounds ZHEJIANG JIANGSHAN CHEMICAL CO (CN) 2005-09-07 CN disclosed