Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28008017 | 0.87 | KDM4E (0.43) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| Hydrochloric Acid SCHEMBL3350621 | 0.83 | KDM4E (0.38) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL22662448 | 0.80 | KDM4E (0.52) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL960674 | 0.80 | KDM4E (0.40) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL6534968 | 0.78 | CYP2C19 (0.62) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL9842065 | 0.78 | LMNA (0.37) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL3465587 | 0.78 | LMNA (0.37) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| Hydrochloric Acid SCHEMBL4137653 | 0.77 | TSHR (0.60) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL83915 | 0.77 | TSHR (0.60) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL5069470 | 0.76 | KDM4E (0.31) | KDM4EHMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102409373-B | Cyanide-free silver electroplating solutions | ROHM AND HAAS COMPANY ELECT MATERIALS | 2015-05-20 | — | — | CN | claimed |
| CN-102409372-B | Method of electroplating silver strike over nickel | ROHM & HAAS ELECT MAT | 2015-02-11 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |
| CN-111615408-A | Method for pneumatically conveying superabsorbent particles | 巴斯夫欧洲公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-106478497-B | Arylamine derivatives as TTX-S blockers | 拉夸里亚创药株式会社 | 2020-05-08 | — | — | CN | disclosed |
| CN-109996778-A | Taste adjusts aldehyde | 高砂香料工业株式会社 | 2019-07-09 | — | — | CN | disclosed |
| CN-109803948-A | Warming sensation compound | 高砂香料工业株式会社 | 2019-05-24 | — | — | CN | disclosed |
| EP-3353178-A1 | NEW BICYCLIC COMPOUNDS AS DUAL ATX/CA INHIBITORS | H. Hoffnabb-La Roche Ag (CH) | 2018-08-01 | — | — | EP | disclosed |
| CN-104860874-B | Bicyclic or tricyclic steric hindrance alkoxyamine and preparation method thereof | 巴斯夫欧洲公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104884538-B | Pigment dispersing agent, the manufacture method of pigment dispersing agent and dispersible pigment dispersion | 大日精化工业株式会社 | 2017-12-15 | — | — | CN | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1509537-B9 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES INC (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| EP-1509537-B1 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES INC (US) | 2007-07-18 | — | — | EP | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| US-5198452-A | Leukotriene antagonist, lipoxygenase or cyclooxygenase inhibitors, antihistamines or antiallergens | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0466125-A2 | Styryl compounds and their pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | KDM4E 3256/4885HMGCR 1715/4885CHRM1 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.