Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | APP | P05067 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | IDH2 | P48735 | 1/20 | 0.54 |
| ▸ | TXN | P10599 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874930 | 0.92 | NFKB1 (0.65) | MEN1KMT2AMAPTMAPK1NFKB1 | |
| SCHEMBL22123529 | 0.87 | ABCG2 (0.58) | MEN1KMT2AMAPTMAPK1NFKB1 | |
| SCHEMBL8525000 | 0.86 | TP53 (0.59) | MEN1KMT2AMAPTAPPNPC1 | |
| SCHEMBL1925527 | 0.85 | MEN1 (0.79) | MEN1KMT2AMAPTMAPK1NFKB1 | |
| SCHEMBL30933599 | 0.84 | APP (0.54) | MEN1KMT2AMAPTMAPK1NFKB1 | |
| SCHEMBL8525007 | 0.84 | MEN1 (0.53) | MEN1KMT2AMAPTMAPK1NFKB1 | |
| SCHEMBL1923883 | 0.84 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1NFKB1 | |
| SCHEMBL27598771 | 0.82 | CDC7 (0.69) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1390952 | 0.82 | KCNH3 (0.64) | MEN1KMT2AMAPTNFKB1APP | |
| SCHEMBL8297647 | 0.81 | TP53 (0.52) | MEN1KMT2AMAPTNFKB1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001442-A1 | TRIAZINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1999-01-14 | — | — | WO | disclosed |