Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583161 | 0.87 | MAPT (0.47) | MAPTALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL27600605 | 0.85 | KMT2A (0.49) | MAPTALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL2143592 | 0.83 | GRIA2 (0.50) | MAPTALDH1A1SNCAATMTDP1 | |
| SCHEMBL27600452 | 0.82 | MAPT (0.41) | MAPTALDH1A1SNCAATMTDP1 | |
| SCHEMBL8529543 | 0.82 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL8529545 | 0.82 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL10473975 | 0.79 | MAPT (0.50) | MAPTALDH1A1SNCAATMTDP1 | |
| SCHEMBL20543943 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1TDP1 | |
| SCHEMBL17484695 | 0.78 | MAPT (0.49) | MAPTALDH1A1SNCAATMTDP1 | |
| SCHEMBL28749966 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1476446-A | Benzodiazepine derivative | ֮����ʽ���� | 2004-02-18 | — | — | CN | disclosed |