Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600108 | 0.83 | PDK2 (0.41) | FABP4ERN1BCAT2IKBKBKDM4E | |
| SCHEMBL27599997 | 0.80 | FABP4 (0.46) | FABP4ERN1BCAT2IKBKBKDM4E | |
| SCHEMBL27599960 | 0.76 | AKR1C2 (0.44) | ERN1BCAT2IKBKBKDM4EALDH1A1 | |
| SCHEMBL25436660 | 0.75 | KDM4E (0.44) | ERN1BCAT2IKBKBKDM4EALDH1A1 | |
| SCHEMBL27600133 | 0.75 | AKR1C2 (0.43) | ERN1BCAT2IKBKBKDM4EALDH1A1 | |
| SCHEMBL30339795 | 0.73 | FABP4 (0.58) | FABP4BCAT2IKBKBPARP1LMNA | |
| SCHEMBL530568 | 0.73 | FABP4 (0.58) | FABP4BCAT2IKBKBPARP1LMNA | |
| SCHEMBL28562251 | 0.72 | BCAT2 (0.47) | BCAT2IKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL27600131 | 0.72 | IKBKB (0.40) | FABP4ERN1BCAT2IKBKBKDM4E | |
| Hydrochloric Acid SCHEMBL28812647 | 0.72 | FABP4 (0.57) | FABP4BCAT2IKBKBPARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1658872-B | Antiallergic agent | INST MED MOLECULAR DESIGN INC | 2010-09-22 | — | — | CN | disclosed |
| CN-1658872-A | Antiallergic agent | INST MED MOLECULAR DESIGN INC (JP) | 2005-08-24 | — | — | CN | disclosed |