Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 5/20 | 0.38 |
| ▸ | CHUK | O15111 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599960 | 0.84 | AKR1C2 (0.44) | AKR1C2AKR1C1BCAT2IKBKBCHUK | |
| SCHEMBL25436660 | 0.83 | KDM4E (0.44) | AKR1C2AKR1C1BCAT2IKBKBCHUK | |
| SCHEMBL27600131 | 0.80 | IKBKB (0.40) | AKR1C2AKR1C1BCAT2IKBKBCHUK | |
| SCHEMBL27600956 | 0.75 | FABP4 (0.39) | BCAT2IKBKBCHUKKDM4EALDH1A1 | |
| SCHEMBL27600108 | 0.75 | PDK2 (0.41) | AKR1C2AKR1C1BCAT2IKBKBKDM4E | |
| SCHEMBL5306730 | 0.74 | AKR1C2 (0.75) | AKR1C2AKR1C1AKR1C3AKR1C4CRHBP | |
| SCHEMBL27599997 | 0.74 | FABP4 (0.46) | BCAT2IKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL28916377 | 0.72 | BCAT2 (0.42) | AKR1C2AKR1C1BCAT2IKBKBCHUK | |
| SCHEMBL3763563 | 0.71 | FABP4 (0.43) | BCAT2IKBKBCHUKKDM4EALDH1A1 | |
| SCHEMBL28013764 | 0.71 | IKBKB (0.49) | BCAT2IKBKBCHUKKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109512805-B | Compounds for the treatment of aquaporin mediated diseases | 埃罗米克斯公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-101849953-B | Inflammatory cytokine release inhibitor | INST MED MOLECULAR DESIGN INC | 2012-04-25 | — | — | CN | disclosed |
| CN-101849953-A | Inflammatory cytokine release inhibitor | INST MED MOLECULAR DESIGN INC | 2010-10-06 | — | — | CN | disclosed |
| CN-100370975-C | Inflammatory cytokine production dissociation inhibitor | INST OF MEDICINE MOLECULAR DES (JP) | 2008-02-27 | — | — | CN | disclosed |
| CN-101125138-A | Inhibitors against the production and release of inflammatory cytokines | INST MED MOLECULAR DESIGN INC (JP) | 2008-02-20 | — | — | CN | disclosed |
| CN-1489458-A | Inflammatory cytokine production dissociation inhibitor | ��ʽ����ҽҩ��������о��� | 2004-04-14 | — | — | CN | disclosed |