Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855424 | 0.92 | NAAA (0.60) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL5039785 | 0.87 | NAAA (0.63) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL5048823 | 0.87 | NAAA (0.63) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL27601086 | 0.87 | NAAA (0.63) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL6718542 | 0.81 | NAAA (0.73) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL28754789 | 0.81 | L3MBTL1 (0.62) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL29300146 | 0.80 | L3MBTL1 (0.60) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL1003239 | 0.78 | NAAA (1.00) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL20216434 | 0.78 | NAAA (1.00) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL8204741 | 0.78 | NAAA (1.00) | NAAAHDAC3HDAC1HDAC2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |