Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872785 | 0.83 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6646832 | 0.81 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL12205820 | 0.77 | MAPT (0.52) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL16933596 | 0.77 | LMNA (0.47) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28750028 | 0.75 | ALDH1A1 (0.55) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28750029 | 0.75 | ALDH1A1 (0.55) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL16841790 | 0.75 | POLB (0.49) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL13996572 | 0.75 | POLB (0.50) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4485170 | 0.75 | ABCB11 (0.56) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2986775 | 0.74 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1500081-A | Thiohydantonins and use thereof for treating diabetes | ʵ���Ҹ���Ү��˾ | 2004-05-26 | — | — | CN | disclosed |