Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752206 | 0.93 | TDP1 (0.49) | SMN1; SMN2ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL6607753 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL6174645 | 0.88 | MAPT (0.52) | SMN1; SMN2ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL9483910 | 0.85 | TDP1 (0.53) | SMN1; SMN2ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL7422213 | 0.83 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL14000151 | 0.83 | TSHR (0.42) | SMN1; SMN2ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL9483914 | 0.83 | TDP1 (0.56) | SMN1; SMN2ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL27583807 | 0.81 | CYP3A4 (0.50) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL6174036 | 0.81 | ADRA2C (0.51) | HPGDMEN1KMT2AACHEMAPT | |
| SCHEMBL14248928 | 0.79 | TDP1 (0.51) | SMN1; SMN2ALDH1A1POLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1473157-A | Amide derivatives | ֮����ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |