Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601299 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAALDH1A1HPGDMEN1 | |
| SCHEMBL7417406 | 0.86 | ALDH1A1 (0.70) | SMN1; SMN2GAAHTTALDH1A1MEN1 | |
| SCHEMBL5807041 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAALDH1A1TSHRGLA | |
| SCHEMBL6901552 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAALDH1A1TSHRGLA | |
| SCHEMBL6609664 | 0.84 | ADRA2C (0.51) | SMN1; SMN2GAAADRA2CHTTALDH1A1 | |
| SCHEMBL9366543 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1TSHRGLA | |
| SCHEMBL8103391 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2GAAHTTALDH1A1MEN1 | |
| SCHEMBL11437661 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAALDH1A1TSHRGLA | |
| SCHEMBL6382412 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAALDH1A1TSHRGLA | |
| SCHEMBL20169531 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114815-B1 | Process to prepare taxol | UPJOHN CO (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1352900-A1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-1352899-A1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-0912504-B1 | Oxazolidine ester | UPJOHN CO (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6307064-B1 | PHENYLISOSERINE ESTER OF SILYLATED BACCATIN III | PHARMACIA & UPJOHN COMPANY | 2001-10-23 | — | — | US | disclosed |
| EP-1114815-A2 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6177573-B1 | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY | 2001-01-23 | — | — | US | disclosed |
| US-6057452-A | Process to prepare taxol | PHARMACIA & UPJOHN COMPANY | 2000-05-02 | — | — | US | disclosed |