Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340992 | 0.93 | MAPK10 (0.58) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL6714765 | 0.86 | CA1 (0.51) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL5347707 | 0.84 | OPRK1 (0.53) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| Hydrochloric Acid SCHEMBL11001196 | 0.83 | OPRK1 (0.52) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL8215360 | 0.81 | MAPK10 (0.62) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL6716640 | 0.79 | KMT2A (0.46) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL6716645 | 0.79 | KMT2A (0.46) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| Hydrochloric Acid SCHEMBL7402058 | 0.78 | SRD5A2 (0.47) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL6718309 | 0.78 | MAPK10 (0.45) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL11065454 | 0.77 | OPRK1 (0.52) | MAPK10OPRK1PDE4DNR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1474812-A | (dihydro) isoquinoline derivatives as phosphodiesterase inhibitors | �ȿˡ��Ŷ��١���ķ������ѧ��˾ | 2004-02-11 | — | — | CN | disclosed |