Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 5/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601351 | 0.93 | MAPK10 (0.52) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL5347707 | 0.91 | OPRK1 (0.53) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| Hydrochloric Acid SCHEMBL11001196 | 0.89 | OPRK1 (0.52) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL8215360 | 0.87 | MAPK10 (0.62) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL6718309 | 0.84 | MAPK10 (0.45) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| Hydrochloric Acid SCHEMBL6718286 | 0.83 | MAPK10 (0.53) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| Hydrochloric Acid SCHEMBL7402058 | 0.82 | SRD5A2 (0.47) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL6714765 | 0.81 | CA1 (0.51) | MAPK10OPRK1PDE4DNR1I2ADORA3 | |
| SCHEMBL2334077 | 0.81 | MAPK10 (0.51) | MAPK10MAPK9MAPK14ALDH1A1PLG | |
| SCHEMBL28531265 | 0.81 | MAPK10 (0.55) | MAPK10OPRK1PDE4DNR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467548-B | Sulfonamide or ketoamide compound and preparation method thereof | 西南交通大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-110467548-A | A kind of sulfonamides or keto acyl aminated compounds and preparation method thereof | UNIV SOUTHWEST JIAOTONG | 2019-11-19 | — | — | CN | disclosed |