SCHEMBL27601447

SCHEMBL27601447

CC(C)[Si](OC(=O)CCCC(=O)Cl)(C(C)C)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 4/20 0.38
LMNA P02545 2/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642052 0.82 LMNA (0.33) TSHRLMNAMAPT
SCHEMBL4644679 0.81 LMNA (0.36) TSHRLMNAMAPT
SCHEMBL15671163 0.80 LMNA (0.47) ALDH1A1TP53TSHRLMNAMAPT
SCHEMBL4644041 0.80 CAMK2A (0.36) TSHRLMNAMAPT
SCHEMBL4647662 0.78 LMNA (0.33) TSHRLMNAMAPT
SCHEMBL4641378 0.78 LMNA (0.37) TSHRLMNAMAPT
SCHEMBL27601413 0.78 ALDH1A1 (0.38) ALDH1A1TP53TSHRLMNA
SCHEMBL4641714 0.78
SCHEMBL25268180 0.77 LMNA (0.58) ALDH1A1TSHRLMNAMAPT
SCHEMBL4645766 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed