SCHEMBL4644041

SCHEMBL4644041

CC(C)[Si](OC(=O)CCCO)(C(C)C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.36
TSHR P16473 2/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 2/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641378 0.94 LMNA (0.37) TSHRLMNAMAPTMAPK1KDM4E
SCHEMBL4645766 0.87
SCHEMBL15671163 0.83 LMNA (0.47) TSHRLMNAMAPTMAPK1KDM4E
SCHEMBL4644687 0.82 LMNA (0.35) CAMK2ATSHRLMNAMAPTMAPK1
SCHEMBL4647662 0.82 LMNA (0.33) TSHRLMNAMAPT
SCHEMBL4642052 0.82 LMNA (0.33) TSHRLMNAMAPT
SCHEMBL25268180 0.80 LMNA (0.58) TSHRLMNAMAPTMAPK1KDM4E
SCHEMBL27601447 0.80 ALDH1A1 (0.40) TSHRLMNAMAPT
SCHEMBL4644679 0.80 LMNA (0.36) TSHRLMNAMAPTMAPK1
SCHEMBL4644943 0.78 CYP19A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed