Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536597 | 0.86 | ALDH1A1 (0.49) | ESR1KDM4EPOLBALDH1A1TSHR | |
| SCHEMBL5542394 | 0.84 | ESR1 (0.54) | ESR1ALDH1A1TSHRTDP1MEN1 | |
| SCHEMBL5539416 | 0.83 | ESR1 (0.50) | ESR1ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL5535885 | 0.82 | ALDH1A1 (0.52) | ESR1ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL5540470 | 0.81 | CA12 (0.50) | ESR1KDM4EPOLBALDH1A1HCRTR1 | |
| SCHEMBL6015765 | 0.78 | PHLPP2 (0.51) | KDM4EPOLBALDH1A1TSHRKDR | |
| SCHEMBL6015975 | 0.76 | GAA (0.53) | ESR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL4243309 | 0.74 | KIF11 (0.48) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6015931 | 0.73 | KMT2A (0.54) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27620060 | 0.73 | KMT2A (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | claimed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | disclosed |