Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499030 | 0.89 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL6503011 | 0.88 | MAPT (0.52) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5496722 | 0.87 | MAPT (0.51) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5492140 | 0.86 | MAPT (0.47) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5487242 | 0.84 | PYGL (0.54) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5491138 | 0.83 | PYGL (0.52) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL6181468 | 0.81 | SMN1; SMN2 (0.50) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5491191 | 0.81 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5495384 | 0.81 | RAB9A (0.56) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5496386 | 0.81 | ACLY (0.52) | MAPTRAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1494539-A | Antagonists of MCP-1 function and methods of use thereof | ̩ | 2004-05-05 | — | — | CN | claimed |
| CN-1494539-A | Antagonists of MCP-1 function and methods of use thereof | ̩ | 2004-05-05 | — | — | CN | disclosed |