Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018005 | 0.81 | FABP4 (0.50) | FABP3FABP4FABP5FABP2HTR6 | |
| Dimethylformamide SCHEMBL27851067 | 0.69 | POLB (0.43) | FABP3FABP4FABP5FABP2HTR6 | |
| SCHEMBL6392957 | 0.69 | PARP1 (0.41) | FABP3FABP4FABP5HTR6KMT2A | |
| SCHEMBL31623977 | 0.69 | KDM4E (0.39) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1490129 | 0.69 | KDM4E (0.39) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6391657 | 0.68 | ERCC1 (0.41) | FABP3FABP4FABP5FABP2POLB | |
| SCHEMBL17687427 | 0.67 | HTR6 (0.41) | FABP3FABP4FABP5FABP2HTR6 | |
| SCHEMBL3564084 | 0.67 | SRC (0.51) | FABP3FABP4FABP5HTR6AGTR1 | |
| SCHEMBL8822466 | 0.67 | GPR3 (0.58) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL17825377 | 0.66 | MEN1 (0.37) | FABP3FABP4FABP5HTR6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1662206-A | Use of thio-2-oxindole derivatives in treatment of skin disorders | WYETH CORP (US) | 2005-08-31 | — | — | CN | disclosed |