Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL27447895 | 0.97 | CES2 (0.54) | CES2LMNAMAPTPOLBHTT | |
| Acetonitrile SCHEMBL28316575 | 0.93 | ALDH1A1 (0.50) | CES2LMNAMAPTPOLBHTT | |
| Dimethylcarbate SCHEMBL28230671 | 0.92 | ALDH1A1 (0.49) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL28247987 | 0.91 | LMNA (0.48) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL11524668 | 0.88 | MAPT (0.59) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL8597900 | 0.88 | TTR (0.51) | LMNAMAPTPOLBHTTSMN1; SMN2 | |
| Morpholine SCHEMBL28838913 | 0.86 | ALDH1A1 (0.56) | CES2LMNAMAPTPOLBHTT | |
| Ethyl Acetate SCHEMBL27570280 | 0.86 | MAPT (0.48) | CES2LMNAMAPTPOLBHTT | |
| Malonic Acid Diethyl Ester SCHEMBL28326884 | 0.85 | MAPT (0.47) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL29355334 | 0.83 | CES2 (0.75) | CES2LMNAMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397358-B | A kind of method of the micro passage reaction synthesis fluoro- 4- of 3- (4- morpholinyl) aniline | 黑龙江鑫创生物科技开发有限公司 | 2018-11-20 | — | — | CN | claimed |
| CN-108431001-A | Ring-fused pyrimidines compound or its salt | 大鹏药品工业株式会社 | 2018-08-21 | — | — | CN | claimed |
| CN-108084165-A | A kind of anticancer swells the preparation method of drug Si Dinibu | 董丹丹 | 2018-05-29 | — | — | CN | claimed |
| CN-107849040-A | tricyclic derivative compound, preparation method thereof, and pharmaceutical composition containing the same | 第药品株式会社 | 2018-03-27 | — | — | CN | claimed |
| CN-104803970-B | Intermediate of Yi Zhong oxazolidinone antimicrobial compounds and preparation method thereof | 四川好医生药业集团有限公司 | 2017-10-27 | — | — | CN | claimed |
| CN-103547565-A | Substituted cyanoaniline compounds, preparation and use thereof | SINOCHEM CORP | 2014-01-29 | — | — | CN | claimed |
| CN-101184487-B | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA NV | 2010-11-03 | — | — | CN | claimed |
| CN-101184487-A | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-21 | — | — | CN | claimed |
| CN-115745868-A | Aluminum ion detection fluorescent probe based on luminescence enhancement | 湖南理工学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-110372666-A | Quinazoline compounds are as tri- inhibition from mutation agent of EGFR and its application | 华东理工大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-110382487-A | Silicon-containing compound for anti-hepatitis c virus infection | 正大天晴药业集团股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-106795118-B | Heterocyclic compound and their purposes as relevant orphan receptor (ROR) the GAMMA-T inhibitor of retinoids | 武田药品工业株式会社 | 2019-10-08 | — | — | CN | disclosed |
| CN-110214136-A | Pyrazole derivatives as MALT1 inhibitor | 詹森药业有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-110177784-A | One kind containing aromatic compound, preparation method, pharmaceutical composition and application | 罗欣药业(上海)有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-101208009-A | Composition for preventing and removing pest | MITSUI CHEMICALS INC (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-101203132-A | Insecticidal and bactericidal composition | MITSUI CHEMICALS INC (JP) | 2008-06-18 | — | — | CN | disclosed |
| CN-101184487-A | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-21 | — | — | CN | disclosed |
| CN-1964629-A | Triazolopyrimidine compounds and their use for controlling harmful fungi | BASF AG (DE) | 2007-05-16 | — | — | CN | disclosed |
| CN-1829512-A | Medicinal composition containing triazole compound | SANKYO CO (JP) | 2006-09-06 | — | — | CN | disclosed |
| CN-1681503-A | Sulphonylpiperidine derivatives containing an aryl or heteroaryl group for use as matrix metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |