Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.50 |
| ▸ | EGFR | P00533 | 10/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.47 |
| ▸ | PRKDC | P78527 | 15/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.47 |
| ▸ | ABL1 | P00519 | 11/20 | 0.47 |
| ▸ | HCK | P08631 | 9/20 | 0.47 |
| ▸ | KDR | P35968 | 9/20 | 0.47 |
| ▸ | MTOR | P42345 | 9/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320501 | 0.82 | SRC (0.55) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL23997145 | 0.82 | SRC (0.55) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL5801898 | 0.79 | SRC (0.54) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL4819181 | 0.79 | NUDT14 (0.66) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL21436578 | 0.77 | PIK3CD (0.65) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL30320603 | 0.77 | PIK3CD (0.65) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL24096509 | 0.74 | SRC (0.79) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL30320468 | 0.74 | SRC (0.79) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL23997251 | 0.74 | CYP1A2 (0.69) | SRCEGFRPIK3CDPRKDCPIK3CA | |
| SCHEMBL24096758 | 0.74 | PIK3CD (0.69) | SRCEGFRPIK3CDPRKDCPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |