Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28264125 | 0.86 | SMN1; SMN2 (0.35) | NPC1RAB9ANOTUMHPGDSMN1; SMN2 | |
| SCHEMBL17994177 | 0.83 | NOTUM (0.48) | NPSR1NPC1RAB9ANOTUMCCNC | |
| Ethoxycarbonyl Group SCHEMBL27588338 | 0.76 | NAMPT (0.35) | NPSR1HRH4HPGDL3MBTL1MAPT | |
| Ethoxycarbonyl Group SCHEMBL27323072 | 0.74 | CYP1A2 (0.43) | NPSR1POLBL3MBTL1MAPTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28015510 | 0.70 | NOTUM (0.31) | NOTUM | |
| Ethoxycarbonyl Group SCHEMBL27686221 | 0.69 | TBXAS1 (0.47) | POLBTP53ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28300783 | 0.69 | TSHR (0.31) | — | |
| Ethoxycarbonyl Group SCHEMBL27720341 | 0.69 | — | — | |
| SCHEMBL27893677 | 0.69 | MTNR1A (0.33) | — | |
| SCHEMBL23997326 | 0.67 | RAB9A (0.42) | NPC1RAB9AHPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491349-C | Antiviral agent | SHIONOGI & CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1558898-A | Antiviral agent | ��Ұ����ҩ��ʽ���� | 2004-12-29 | — | — | CN | disclosed |