Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349460 | 0.85 | TSHR (0.42) | L3MBTL1P2RX7HDAC1HDAC6KDM4E | |
| SCHEMBL12836123 | 0.83 | P2RX7 (0.40) | ADRA2AADRA2BADRA2CP2RX7GRM2 | |
| SCHEMBL10349464 | 0.81 | MAPT (0.40) | P2RX7HDAC1HDAC6KDM4ESMN1; SMN2 | |
| SCHEMBL6075377 | 0.80 | TAAR1 (0.50) | L3MBTL1ADRA2AADRA2BADRA2CP2RX7 | |
| SCHEMBL2760706 | 0.80 | NNMT (0.51) | L3MBTL1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL4531132 | 0.80 | CYP2C19 (0.48) | P2RX7CYP2C19SMN1; SMN2HTTLMNA | |
| SCHEMBL10349461 | 0.80 | KDM4E (0.42) | P2RX7HDAC1HDAC6CYP2C19KDM4E | |
| SCHEMBL17664582 | 0.77 | CYP3A4 (0.40) | ADRA2AADRA2BADRA2CP2RX7GRM2 | |
| SCHEMBL1495530 | 0.77 | CYP3A4 (0.40) | ADRA2AADRA2BADRA2CP2RX7GRM2 | |
| SCHEMBL12352043 | 0.77 | LMNA (0.47) | ADRA2AADRA2BADRA2CP2RX7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262766-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |